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Selisistat S-enantiomer
CAS No. 848193-68-0
Selisistat S-enantiomer ( EX-527(S); (S)-Selisistat; EX 527(S) )
Catalog No. M19374 CAS No. 848193-68-0
EX-527 S-enantiomer is the S-enantiomer of EX-527,with an IC50 of 123 nM for SIRT1.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 203 | Get Quote |
|
| 5MG | 314 | Get Quote |
|
| 10MG | 447 | Get Quote |
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| 25MG | 714 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSelisistat S-enantiomer
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NoteResearch use only, not for human use.
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Brief DescriptionEX-527 S-enantiomer is the S-enantiomer of EX-527,with an IC50 of 123 nM for SIRT1.
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DescriptionEX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3.
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SynonymsEX-527(S); (S)-Selisistat; EX 527(S)
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSIRT1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number848193-68-0
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Formula Weight248.71
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Molecular FormulaC13H13ClN2O
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Purity98%
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SolubilityDMSO : ≥ 100 mg/mL; 402.07 mM
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SMILESC1C[C@@H](C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
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Chemical Name(S)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
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